Management of HAE

Management of HAE can be divided into various approaches. The aim of treatment of acute attacks, also referred to as ‘on demand therapy’ is to minimize their severity, including potentially fatal upper airway edema, and associated impairment of Quality of Life (QoL). Short term prophylaxis (STP) refers to treatment meant to minimize the risk of attacks when avoidance of potential and known triggers is not possible. Long term prophylaxis (LTP) refers to ongoing treatment of HAE aimed at minimizing the overall number, frequency and/or severity of attacks. The details of specific therapies for these treatment approaches are reviewed in the current Canadian Hereditary Angioedema Guidelines.