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Immunoreactive precipitation of C1 inhibitor protein from plasma of normal subjects and of patients with hereditary angioedema after isoelectric focusing

Oct;24(10):719-722

C1-inhibitor is an acid glycoprotein, isoelectric point 3.5-3.6. Plasma of some patients with a variant form of hereditary angioedema contains high levels of functionless C1-inhibitor-albumin complex with an isoelectric point at 4.5-4.6. Therapy with Danazol, which increases C1-inhibitor levels, does not modify the isoelectric focusing pattern of such protein in patients with hereditary angioedema.

Available online at: http://www.researchgate.net/publication/19379027_Immunoreactive_Precipitation_of_C1_Inhibitor_Protein_from_Plasma_of_Normal_Subjects_and_of_Patients_with_Hereditary_Angioedema_after_Isoelectric_Focusing

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