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Plasma kinin activation in tranexamic acid treated patients with hereditary angioneurotic edema

Jul 28;262(2):153-156

Plasma kinin formation after in vitro activation of factor XII in the coagulation system was examined in 4 patients with hereditary angioneurotic edema. Compared to controls activationcurves showed a steeper increase and higher maximum levels. Administration of tranexamic acid to the patients resulted in partial normalisation of plasma kinin activation.

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