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Hereditary angioedema-Experience of the Argentine Allergy and Immunology Institute

Since the detection of the first patient with hereditary angioedema (HA) in 1978, 88 new patients belonging to 16 families have been referred to our clinic. Eighty patients had Type I disease, 5 Type II, and 3 Type III (secondary). We describe the clinical onset, frequent complications, diagnostic tests of the complement system, and abnormalities of the coagulation pathway linked to complement activation. Particular attention was paid to family members who could present succedaneum symptoms. The results of danazole and other therapies and protective and preventive treatment for surgery also are discussed.

Available online at: http://www.elsevier.es/en-revista-allergologia-et-immunopathologia-105-articulo-hereditary-angioedema-long-term-follow-up-of-10017977

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