Hereditary angio-oedema treated with E-aminocaproic acid

SUMMARY.— Two brothers with hereditary angio-oedema have been studied, the only 2 cases among 227 patients with angio-oedema seen in 10 years. The absence of the inhibitor of the activated first component of complement in their serum confirmed the diagnosis. In a double blind trial their symptoms were partially controlled by ε – aminocaproic acid, although there were no consistent changes in the serum complement levels.

Available online at: http://onlinelibrary.wiley.com/doi/10.1111/j.1365-2133.1969.tb15938.x/abstract (small fee)